Gush was born in 1981 in Pietermaritzburg and lives in Johannesburg. He completed postgraduate studies at the Hoger Instituut van Schone Kunsten in Ghent, Belgium, in 2008, and was a 2011 Fellow at the Gordon Institute for Performing and Creative Arts, University of Cape Town.
Solo shows include Simon Gush: Sala10 at the Museo Universitario Arte Contemporáneo, Mexico (2020); Al final del trabajo at Ex Teresa Arte Actual, Mexico (2018); After Work at Galerie Jette Rudolph in Berlin (2015); 9 o'clock at the National Arts Festival, Makhanda (2015); Red at the Goethe-Institut, Johannesburg (2014) and at Anne Bryant Art Gallery in East London and ArtEC in Port Elizabeth (2015); 1st and 3rd at Galerie West, The Hague, and 4 for Four at S.M.A.K., Ghent (both 2010); in addition to seven solo exhibitions at Stevenson, Cape Town and Johannesburg, between 2007 and 2019.
Group shows include Sounding the Land, Makhanda National Arts Festival, (2020); Every Leaf Is an Eye, Göteborgs Konsthall, Sweden (2019); Buiten at S.M.A.K, Ghent, Belgium (2018); African Metropolis. An Imaginary City at MAXXI, Rome (2018); Of Traps and Tropes, 1st Kerkennah International Festival of Photography and Visual arts, Tunisia (2018); Affinities, or The Weight of Cinema at the National Gallery of Art, Washington DC (2018); Deconstructed Spaces, Surveyed Memories at the 11th Rencontres de Bamako, Mali (2017); Avant Noir, vol 3, ICA, London (2017); Focus South Africa, Vision du Réel, Nyon (2017); International Short Film Festival, Oberhausen (2017); Recent Histories - New African Photography at the Walther Collection in Neu-Ulm (2017); Afriques Capitales at La Villette, Paris (2017); I Love You Sugar Kane at the Institute of Contemporary Art Indian Ocean, Mauritius (2016); While You Were Out at the Museum of Fine Arts Boston (2015); The Films Will Always Be You: South African Artists on Screen at Tate Modern in London (2015); Artists Engaged? Maybe at Fundação Calouste Gulbenkian, Lisbon (2014); My Joburg at La Maison Rouge, Paris, and the Staatliche Kunstsammlungen in Dresden (2013); Halakasha at the Standard Bank Gallery in Johannesburg in 2010; and 1910-2010: From Pierneef to Gugulective at the Iziko South African National Gallery in Cape Town in 2010; among others. Gush has been included in biennales including the Biennale für aktuelle Fotografie, Heidelberg, Ludwigshafen and Mannheim (2017) Dak'Art, Senegal, in 2016; Bamako, Mali, in 2015; Montevideo, Uruguay, in 2014; and Luleå, Sweden, in 2009.
Gush was awarded the Jury Prize at the Bamako Encounters Biennale in 2015.